Treatment of Ebola Virus

Symptoms of Ebola virus disease (EVD) are treated as they appear. When used early, basic interventions can significantly improve the chances of survival. These include:

  • Providing fluids and electrolytes (body salts) through infusion into the vein (intravenously).

  • Offering oxygen therapy to maintain oxygen status.

  • Using medication to support blood pressure, reduce vomiting and diarrhea and to manage fever and pain.

  • Treating other infections, if they occur.

Antiviral Drugs

There is currently no antiviral drug licensed by the U.S. Food and Drug Administration (FDA) to treat EVD in people.

During the 2018 eastern Democratic Republic of the Congo outbreak, four investigational treatments were initially available to treat patients with confirmed Ebola. For two of those treatments, called regeneron (REGN-EB3) and mAb114, overall survival was much higher. These two antiviral drugs currently remain in use for patients with confirmed Ebola.

Drugs that are being developed to treat EVD work by stopping the virus from making copies of itself.

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